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Effect of Caralluma Fimbriata Plant Extract on Appetite – a Case Study

by admin on October 17, 2010

Caralluma fimbriata an edible cactus, used by tribal Indians to suppress hunger and enhance endurance. The effect of Caralluma extract was assessed in overweight individuals by a placebo controlled randomized trial. Fifty adult men and women (25–60 years) with a body mass index (BMI) greater than 25 kg/m2 were randomly assigned into a placebo or experimental group; the latter received 1 g of Caralluma extract per day for 60 days. All subjects were given standard advice regarding a weight reducing diet and physical activity.

At the end of 30 and 60 days of intervention, blood glucose and lipids, anthropometric measurements, dietary intake and assessment of appetite was performed. Waist circumference and hunger levels over the observation period showed a significant decline in the experimental group when compared to the placebo group. While there was a trend towards a greater decrease in body weight, body mass index, hip circumference, body fat and energy intake between assessment time points in the experimental group, these were not significantly different between experimental and placebo groups. Caralluma extract appears to suppress appetite, and reduce waist circumference when compared to placebo over a 2 month period.

The Caralluma extract was made from the aerial parts of the plant with aqueous alcohol which was 40% aqueous (40 parts of alcohol and 60 parts of water). About 12 kg of dried herb was obtained from 100 kg of the fresh plant, which gave a final yield of 1 kg of the extract. It was then purified, granulated and filled in capsules to deliver 500 mg
of the extract.

You can read the full case study and research here

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